- Basic information
- CohesinDB ID: CDBP00416044
- Locus: chr21-28805505-28806589
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Data sourse: ENCSR000EFJ, ENCSR230ZWH, ENCSR000HPG, ENCSR917QNE, GSE206145, GSE206145-NatGen2015, GSE165895
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Cell type: RPE, Fibroblast, IMR-90, Liver, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 71%,
"7_Enh": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, E2F7, SOX2, NME2, FOXA1, ATF3, ZFP64, ATF4, NFE2L2, ESR1, USF2, CTCF, TCF12, JUN, EP300, ZBTB20, GATA6, SOX6, TEAD4, KMT2B, POU5F1, DUX4, HOXC5, MYC, EOMES, RAD21, GRHL3, RXRA, STAT3, IKZF1, RCOR1, NR2F6, NR3C1, CEBPB, CREB1, EZH2, EBF3, HDAC2, GATA2, MXI1, EZH2phosphoT487, SMAD3, SMARCC1, RUNX2, SMAD2, GATA4, ZNF184, PBX4, BACH1, ARNT, ATF2, HMBOX1, SMAD4, PBX3, CBFA2T3, FOS, MED1, C11orf30, MAFK, SP1, USF1, BCL11A, HNF4A, REST, NCOR2, PPARG, FOXA2, CREM, FOXF1, HOXB13, YY1, RELA, JUNB, GATA3, TAL1, MAX, GATA1, NR2F2, ZNF334, NFKB1, BHLHE40, AR, NOTCH3, BRD4, JUND, MAZ, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): LTN1,GRIK1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops