- Basic information
- CohesinDB ID: CDBP00416045
- Locus: chr21-28818509-28819160
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Data sourse: GSE206145-NatGen2015, GSE165895
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Cell type: Fibroblast, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SA1,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 71%,
"5_TxWk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, PPARG, XBP1, HOXB13, SMARCC1, TWIST1, ERG, ZNF300, RELA, ZNF384, JUNB, RUNX2, RXRA, CBFB, GATA3, ATF2, MED1, CBX2, NR3C1, ELF1, NR2F2, TP53, TP73, TCF12, EP300, SP1, AR, PAX3-FOXO1, GATA2, ZNF182, EGLN2, NOTCH3, BRD4
- Target gene symbol (double-evidenced CRMs): GRIK1,LTN1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops