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Basic information

CohesinDB ID: CDBP00416075

Locus: chr21-28931049-28931107

Data sourse: GSE120943, GSE98367

Cell type: Monocytes, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 68% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 55%, "4_Tx": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, SOX2, NME2, XBP1, FOXA1, NFIC, ZBTB44, ZNF189, LMO2, ESR1, CTCF, BAF155, MNT, ZNF423, ZNF528, NANOG, ZNF778, TOP2A, ZBTB17, DUX4, ZBTB48, ERG2, ERG, MYC, RXRA, STAT3, NKX3-1, CEBPB, CREB1, KLF8, GRHL2, FEZF1, GATA2, RUNX1, CEBPA, LDB1, ERG3, SMARCC1, ZNF18, PRDM10, ZNF792, ZNF35, RUNX2, OSR2, ARNT, PBX4, SUPT5H, CHD1, MED1, ZXDB, PIAS1, NUP98-HOXA9, RBM22, BCL11A, HNF4A, ARID1A, PHIP, FOXP1, PRDM6, ZNF394, FOXA2, SS18, ZNF692, ZBTB33, HOXB13, ZNF580, RELA, NEUROD1, ISL1, GATA3, TAL1, GATA1, TLE3, CEBPG, BCL11B, SP7, NR2F2, TCF7L2, NEUROG2, TP53, PKNOX1, PHOX2B, ZNF843, AR, ZBTB42, BRD4, SCRT1, ZZZ3

Target gene symbol (double-evidenced CRMs): LTN1,LINC00113

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000225298, ENSG00000198862,

eachgene

Deatailed information for cohesin site CDBP00416075