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Basic information

CohesinDB ID: CDBP00416077

Locus: chr21-28944300-28944655

Data sourse: ENCSR230ZWH, ENCSR000BLY, ENCSR917QNE

Cell type: Liver, SK-N-SH

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 68% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 55%, "5_TxWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, CEBPA, FOXA2, EBF1, HMG20A, SOX13, NME2, SOX2, HNF1A, POU5F1, DUX4, STAT1, FOXA1, ZBTB33, HOXB13, ERG, YY1, RELA, KDM1A, TFAP4, JUNB, ATF3, MYC, GATA4, RAD21, PRDM1, PBX4, DAXX, RXRA, GATA3, GABPA, TAL1, PBX3, MAX, NKX3-1, FOS, SUPT5H, GATA1, NR2F6, MED1, VDR, TLE3, NR3C1, CEBPB, GFI1B, NR2F2, CEBPD, KMT2A, ETV1, TCF7L2, PIAS1, HNF1B, JUN, ELF3, TCF12, SP1, BAF155, TBX21, ZNF664, HNF4A, IRF1, SOX5, AR, HDAC2, GATA2, REST, EGR1, BRD4, JUND, FOXP1, FOXA3, ZZZ3

Target gene symbol (double-evidenced CRMs): LTN1,LINC00113

Function elements

Human SNPs: .

Number of somatic mutations (coding): 93

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000225298, ENSG00000198862,

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Deatailed information for cohesin site CDBP00416077