- Basic information
- CohesinDB ID: CDBP00416087
- Locus: chr21-28998650-28998885
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Data sourse: GSE206145-NatGen2015, GSE86191
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Cell type: Fibroblast, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 69%,
"5_TxWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXA2, BRD3, POU5F1, TOP2A, MEIS2, ZNF317, ZBTB48, DUX4, FOXF1, ZNF205, PBX2, ERG, ZBTB2, ZEB2, MAX, IKZF1, ETV1, PKNOX1, CTCF, ZNF445, ZBTB7A, FOXP1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: Liver_enzyme_levels_(gamma-glutamyl_transferase)
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
- Related loop:
chr21:17775000-17800000~~chr21:29000000-29025000,
chr21:25325000-25350000~~chr21:29000000-29025000,
chr21:25350000-25375000~~chr21:28975000-29000000,
chr21:25725000-25750000~~chr21:28975000-29000000,
chr21:25725000-25750000~~chr21:29000000-29025000,
chr21:28991455-28993844~~chr21:29023842-29026326,
chr21:28991517-28993800~~chr21:29024190-29026094,
chr21:28991528-28993711~~chr21:29024204-29026148,
chr21:28991579-28993764~~chr21:29023633-29025850,
chr21:28991614-28993817~~chr21:29023881-29026318,
chr21:28991807-28993775~~chr21:29023855-29025783,
chr21:29002049-29004026~~chr21:29018446-29019818,