- Basic information
- CohesinDB ID: CDBP00416165
- Locus: chr21-29247845-29249166
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Data sourse: GSE98367, GSE206145-NatGen2015, GSE62063, GSE120943, GSE103477, GSE126755
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Cell type: MDM, Fibroblast, Monocytes, Neutrophil, Macrophage, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: NIPBL,Rad21,SMC1,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
72% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 79%,
"7_Enh": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, PGR, SMC1A, STAT1, MEF2C, CDK9, ERG, MEF2A, RELA, ZNF384, JUNB, NFIC, RAD21, BATF3, STAT3, MAX, FOS, CDK8, MED1, NR3C1, CEBPB, JMJD1C, KMT2A, TCF7L2, NFKB1, STAT5A, SP1, SPI1, BCL11A, EHF, AR, IRF1, TRIM24, EGR1, FLI1, BRD4, JUND
- Target gene symbol (double-evidenced CRMs): BACH1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops