- Basic information
- CohesinDB ID: CDBP00416172
- Locus: chr21-29261470-29262539
-
Data sourse: GSE206145-GSE177045, GSE98367, GSE138405, GSE206145-NatGen2015, GSE120943, ENCSR000EDE, GSE126990, GSE108869, ENCSR000ECS
-
Cell type: MCF-7, Hela-Kyoto, Fibroblast, Monocytes, HeLa-S3, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
-
Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 88%,
"7_Enh": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXA2, LDB1, TOP2A, NME2, DUX4, SMAD3, FOXA1, FOXF1, HOXB13, HNRNPK, RELA, JUNB, MYC, RAD21, DAXX, ARNT, HIF1A, PBX4, OTX2, NRF1, STAT3, MAX, TP63, FOS, CHD1, MITF, KLF4, CEBPB, KLF5, NFKB1, JUN, EP300, EHF, AR, EGLN2, ZNF366, ZHX1, HSF1, BRD4, JUND, TFAP2C
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops