- Basic information
- CohesinDB ID: CDBP00416226
- Locus: chr21-29432958-29434913
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Data sourse: GSE206145-GSE177045, GSE138405, ENCSR879KXD, GSE73207, ENCSR703TNG, GSE126990, GSE115602
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Cell type: K-562, TF-1, Hela-Kyoto, MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 76%,
"5_TxWk": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, ZSCAN5C, HMGN3, FOXA1, PRDM1, SMARCE1, TEAD1, TRIM28, ESR1, JUN, EP300, BAF155, DPF2, PAX8, SOX6, TEAD4, TFAP2C, POU2F2, BRD3, RUNX1T1, CTBP1, ZBTB17, DUX4, ERG, SMARCA4, ARID1B, GRHL3, FOXK2, STAT3, NKX3-1, IKZF1, RCOR1, NR3C1, CEBPB, CREB1, FEZF1, GRHL2, TRPS1, SPI1, KDM5A, HDAC2, GATA2, CBX1, CEBPA, HDAC1, AFF4, SMAD3, ZXDC, CREBBP, ZNF35, CDK6, GATA4, OSR2, GR, ARNT, ZNF10, MED1, ZXDB, PIAS1, NCOA1, STAT5A, TFAP2A, POU2F3, PHIP, FOXP1, PRDM6, FOXA2, FOXF1, HOXB13, KDM1A, RELA, NEUROD1, HIF1A, OTX2, GATA3, ZNF143, TCF7L2, PKNOX1, BHLHE40, AR, YAP1, EGLN2, BRD4, JUND, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops