Deatailed information for cohesin site CDBP00416270


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  • Basic information
  • CohesinDB ID: CDBP00416270
  • Locus: chr21-29614403-29614741
  • Data sourse: GSE206145, GSE206145-NatGen2015, GSE111913
  • Cell type: RPE, Fibroblast, RT-112
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.967
  • Subunit: Rad21,SA2,SMC1
  • CTCF binding site: non-CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 37% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): False
  • Chromatin annotation: "15_Quies": 92%, "5_TxWk": 5%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOSL1, CBFA2T2, CHD8, BCL6, FOXA2, POU5F1, HDAC1, CBX3, NME2, XBP1, MTA2, FOXA1, ZBTB33, ARID3A, HOXB13, ERG, ZBTB2, ZNF384, JUNB, ATF3, SMARCA4, GATA4, ARID1B, PRDM1, ARNT, HMBOX1, BATF, STAT3, PAX5, SMARCE1, CBFA2T3, GATA1, IKZF1, TAL1, TERF2, NR2F6, DACH1, RCOR1, ZNF143, CEBPG, CEBPB, ZNF592, NR2F2, CEBPD, PML, TRIM28, NR2F1, PIAS1, EZH2, XRCC5, PKNOX1, STAT5A, TCF12, BAF155, EP300, AR, GATA6, IRF1, DPF2, HDAC2, GATA2, ZBTB7A, NCOR1, BRD4, JUND, ILF3, HEXIM1-CDK9, TEAD4, ADNP
  • Target gene symbol (double-evidenced CRMs): GRIK1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 28
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops

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