- Basic information
- CohesinDB ID: CDBP00416274
- Locus: chr21-29635021-29635975
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Data sourse: ENCSR153HNT, ENCSR879KXD
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Cell type: K-562
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
37% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 92%,
"7_Enh": 3%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NME2, FOXA1, RXRB, MLL4, HDGF, PAX5, TEAD1, E2F5, LMO2, OCA2, MED26, HDAC8, E4F1, SOX5, PYGO2, E2F4, KMT2B, GATAD2A, ZNF263, POU5F1, TOP2A, CTBP1, DUX4, STAT1, SAP130, ERG, ZBTB21, PAX6, EZH1, SMARCA4, RFX1, FOXK2, ZNF197, RCOR1, NR2F6, NFRKB, CEBPB, CREB1, GABPB1, ELF4, ZHX2, MIXL1, GATA2, ZNF644, SIX2, FLI1, HCFC1, MXI1, NR2C2, RELB, EP400, RUNX1, HDAC1, CEBPA, NKX2-2, CRY1, SMARCC1, PRDM10, ZBTB2, TFDP1, ELK1, ATF2, FOXM1, FOXJ2, ZNF584, GMEB1, PML, PIAS1, SMAD1, C11orf30, EVI1, STAT5A, GSPT2, RBM25, AFF1, MBD2, NFATC3, CBFA2T2, MEF2B, CBX3, CREM, CHD2, NFATC1, WT1, MEF2C, JUNB, NEUROD1, ZFP36, BATF, SPIB, PLAG1, KLF4, ZKSCAN8, MED, ELF3, RXR, HSF1, NCOR1, ILF3, ADNP, ZNF316, FOSL1, SMARCA2, XBP1, HNF1A, KDM4B, PBX2, ATF3, RUNX3, DPF1, ZSCAN4, MITF, BACH2, JMJD1C, INTS11, MAF, ELF1, RBM39, SMAD5, JUN, CTCF, MNT, DPF2, IRF4, DDX20, PDX1, RBPJ, TFAP2C, MTA2, ZBTB17, ZBTB48, NONO, NBN, PHB2, LHX2, RXRA, BATF3, NKX3-1, LEF1, TEAD2, VDR, NR3C1, ESRRA, KMT2A, ZBTB11, TBL1XR1, ARHGAP35, GRHL2, ZSCAN29, SMARCA5, NFIL3, CC2D1A, LDB1, EZH2phosphoT487, AFF4, SOX13, ZMIZ1, ZNF18, ARNT, BACH1, DAXX, PRDM9, ZEB2, HMBOX1, NFYA, ETV6, PBX3, ZNF10, TEAD3, DIDO1, TAF7, TBX5, USF1, BCL11A, SP1, ATF7, ASH2L, SMC3, STAT2, MLLT1, TRP47, MTA3, EBF1, MEIS1, MAFF, ZKSCAN1, KDM1A, GATA3, TAL1, ZNF143, MTA1, TP53, ZNF334, NFKB1, PHOX2B, BRD2, TBX21, EGR1, RNF2, IKZF2, BRD4, JUND, CUX1, IRF9, CBX5, ZNF496, SOX2, UBTF, TFAP4, BMI1, CHD7, ATF4, MXD4, ZNF189, SMARCE1, KLF6, NFE2L2, ESR1, TP73, KLF1, E2F6, TRIM24, GTF2F1, POU2F2, ELK4, ERG2, TBP, HOXC5, SMARCC2, ETS1, MYC, ARID1B, NKX2-1, GABPA, STAT3, IKZF1, EZH2, NFE2L1, SPI1, HDAC2, INTS13, TAF9B, NCOA2, GTF2A2, BCL6, SIN3A, ERG3, MEF2A, CREBBP, ZNF384, RARA, SMAD4, CBFA2T3, CDK8, ZEB1, ZMYM3, NCOA1, ZNF22, MAFK, NR4A1, REST, HNRNPLL, HOXA9, BCOR, FOXP1, NCOR2, ILK, PTTG1, PPARG, TBL1X, GTF2B, TCF7, ZNF318, RELA, TARDBP, CHAMP1, SKIL, MGA, MAX, ZNF592, GFI1B, NR2F1, NEUROG2, TCF7L2, KDM5B, PKNOX1, MYOD1, T, AR, YAP1, ZNF395, AHR, FOSL2, HMG20A, HMGN3, MEIS2, SUZ12, RBFOX2, LYL1, NFIC, PRDM1, MECOM, HDAC3, ZNF736, CDX2, ZNF629, TRIM28, BCLAF1, ETV1, RCOR2, HNF1B, MLL, USF2, TCF12, EP300, GATA6, SOX6, CREB3, RAD51, E2F1, TEAD4, FOXA3, ZNF175, EHMT2, EED, CHD8, MYCN, RUNX1T1, ID3, HINFP, ZNF205, ARID3A, ZNF300, ASCL1, RAD21, GRHL3, PROX1, XRCC5, NFE2, ZNF639, ARNTL, ZNF750, HES1, IRF1, ZGPAT, MRTFB, ZIM3, ATF1, MAFG, SMC1A, CBX1, SIRT6, ZFX, SMAD3, TWIST1, NSD2, IRF2, NOTCH1, BRD9, RUNX2, CDK6, GATA4, ZNF184, NRF1, NR2C1, FOS, SUPT5H, MED1, CEBPD, MYB, VEZF1, L3MBTL2, KLF16, NUP98-HOXA9, ZBTB7A, CCNT2, POU2F3, TCF3, SKI, KLF13, FOXA2, RBBP5, E2F8, ZBED1, ZBTB33, CDK9, HOXB13, ZNF589, YY1, ZNF148, HIF1A, OTX2, ZNF740, GATA1, HAND2, TLE3, CEBPG, NCOA3, NR2F2, ZNF83, BHLHE40, PTRF, TAF1, ZBTB40, MYNN, NOTCH3, CLOCK, MAZ, MEF2D, ZNF24
- Target gene symbol (double-evidenced CRMs): GRIK1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 35
- Number of somatic mutations (non-coding): 4
- Related genes and loops