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Basic information

CohesinDB ID: CDBP00416305

Locus: chr21-29805135-29805399

Data sourse: ENCSR153HNT, GSE73207

Cell type: K-562, TF-1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 28% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 85%, "14_ReprPCWk": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CBFA2T2, CHD8, FOXA2, HDAC1, CREM, CRY1, ERF, XBP1, DUX4, FOXA1, PBX2, HOXB13, ZKSCAN1, ERG, KDM1A, RELA, ATF3, MYC, BRG1, RFX1, GRHL3, HIF1A, ATF2, GABPA, CBFA2T3, NKX3-1, GATA1, ZNF143, MITF, RCOR1, ARNTL, TLE3, CEBPG, NR3C1, CDX2, GFI1B, TRIM28, CREB1, PIAS1, NFE2L2, ETV1, EZH2, OCA2, GRHL2, SETDB1, NFKB1, PHOX2B, JUN, BAF155, BHLHE40, AR, PAX3-FOXO1, GATA2, ARID1A, SIX2, ATF7, ASH2L, JUND, FOXP1, ATF1, PDX1, AHR

Target gene symbol (double-evidenced CRMs): BACH1,GRIK1,TIAM1

Function elements

Human SNPs: Breast_cancer

Number of somatic mutations (coding): 56

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000156273, ENSG00000171189, ENSG00000156299,

eachgene

Deatailed information for cohesin site CDBP00416305