- Basic information
- CohesinDB ID: CDBP00416322
- Locus: chr21-29904635-29905280
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Data sourse: ENCSR000BLD, GSE67783, ENCSR000BKV, GSE72082, GSE138405, GSE25021, ENCSR000BLY, ENCSR879KXD, ENCSR000BLS, GSE105028, ENCSR000ECE, ENCSR054FKH, GSE131606, GSE97394
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Cell type: MCF-7, H1-hESC, Hela-Kyoto, Hep-G2, DKO, HUES64, SK-N-SH, K-562, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
28% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 84%,
"7_Enh": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, GLIS1, NFIA, FOSL1, PGR, CHD8, PPARG, ZNF283, BRD3, CREM, ID3, SOX13, ZFX, XBP1, ZBTB17, SMAD3, FOXA1, ARID3A, HOXB13, ERG, KDM1A, RELA, JUNB, ATF3, RUNX2, MYC, NFIC, FOXP2, RAD21, DAXX, ARNT, HIF1A, ATF4, GABPA, MGA, STAT3, MAX, FOS, ZNF143, MITF, DACH1, MED1, ARNTL, NR3C1, CEBPG, CEBPB, GFI1B, ELF1, ETV1, NR2F1, SMAD1, STAG1, EZH2, ESR1, TP53, MED26, L3MBTL2, JUN, BRD2, ELF4, CTCF, AR, PAX3-FOXO1, IRF1, GATA2, E2F6, REST, TRIM24, EGLN2, NOTCH3, BRD4, ILF3, JUND, ZNF528, MAZ, MRTFB, SMC3, EHMT2, TFAP2C
- Target gene symbol (double-evidenced CRMs): GRIK1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 28
- Number of somatic mutations (non-coding): 0
- Related genes and loops