- Basic information
- CohesinDB ID: CDBP00416327
- Locus: chr21-29943742-29944359
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE72082, ENCSR000FAD, ENCSR000EGW, ENCSR000BLY, GSE105028, GSE111537, GSE131606, GSE108869, GSE25021, ENCSR917QNE, GSE143937, ENCSR000BKV, GSE138405, GSE101921, GSE138105, GSE130135, ENCSR703TNG, GSE106870, GSE116344, GSE145327, ENCSR000EEG, ENCSR879KXD, ENCSR000BLS, ENCSR000ECE, ENCSR000EHX, GSE97394, ENCSR000BTQ, ENCSR167MTG, ENCSR000EDE, GSE68388, GSE126990, GSE50893, ENCSR000ECS, GSE131577
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Cell type: RH4, GM2610, SLK, CVB-hiPSC, CVI-hiPSC, Liver, HuCC-T1, H9-hESC, GM2630, HMEC, GM12890, HeLa-S3, K-562, DKO, H1-hESC, GM2588, SK-N-SH, HUES64, MCF-7, Hela-Kyoto, HL-60, MCF-10A, HEK293T, Hep-G2, GM19238, OCI-AML-3
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 15% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.711
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
28% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 52%,
"14_ReprPCWk": 44%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMC1A, CEBPA, STAG2, SRF, ZNF654, TRIM22, HOXB13, YY1, ZBTB2, RAD21, ARNT, ZNF10, ZNF143, CREB1, EZH2, KDM5B, ESR1, CTCF, REST, EGLN2, SMC3, ZNF24, STAG1
- Target gene symbol (double-evidenced CRMs): GRIK1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 8
- Related genes and loops
- Related gene:
ENSG00000171189,
- Related loop:
chr21:29575000-29600000~~chr21:29925000-29950000,
chr21:29925000-29950000~~chr21:30025000-30050000,
chr21:29925000-29950000~~chr21:30175000-30200000,
chr21:29925000-29950000~~chr21:30200000-30225000,
chr21:29925000-29950000~~chr21:30250000-30275000,
chr21:29925000-29950000~~chr21:30400000-30425000,
chr21:29943210-29945043~~chr21:30193229-30195738,
chr21:29943210-29945043~~chr21:30257090-30259197,
chr21:29943256-29945015~~chr21:30194046-30195747,
chr21:29943274-29945035~~chr21:30193637-30195774,
chr21:29943381-29944811~~chr21:30194078-30195728,
chr21:29943482-29944650~~chr21:30194059-30195711,