- Basic information
- CohesinDB ID: CDBP00416339
- Locus: chr21-30071621-30073040
-
Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, ENCSR000FAD, GSE72082, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE103477, GSE111537, GSE131606, GSE108869, GSE25021, ENCSR917QNE, GSE115602, GSE93080, GSE67783, ENCSR000BKV, GSE115250, GSE138405, GSE76893, GSE101921, ENCSR198ZYJ, GSE138105, ENCSR703TNG, GSE106870, GSE116344, GSE145327, GSE85526, ENCSR000ECE, GSE97394, GSE55407, ENCSR000BTQ, GSE105004, GSE131956, GSE111913, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS
-
Cell type: RH4, GM2610, SLK, CVB-hiPSC, Liver, HuCC-T1, H9-hESC, HMEC, HEKn, HeLa-S3, K-562, DKO, H1-hESC, GM12878, GBM39, SK-N-SH, RT-112, THP-1, HUES64, MCF-7, Hela-Kyoto, MCF-10A, Neurons-H1, HeLa, TC-71, OCI-AML-3, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 19% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.700
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
-
CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
24% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 87%,
"7_Enh": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: NANOG, ZNF143, SP140, NOTCH3, WT1, SETDB1, HOXB13, MITF
- Target gene symbol (double-evidenced CRMs): GRIK1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 8
- Related genes and loops
- Related gene:
ENSG00000171189,
- Related loop:
chr21:29900000-29925000~~chr21:30050000-30075000,
chr21:30050000-30075000~~chr21:30150000-30175000,
chr21:30050000-30075000~~chr21:30175000-30200000,
chr21:30050000-30075000~~chr21:30400000-30425000,
chr21:30050000-30075000~~chr21:31075000-31100000,
chr21:30050000-30075000~~chr21:31575000-31600000,
chr21:30050000-30075000~~chr21:31600000-31625000,
chr21:30070984-30073381~~chr21:30193229-30195738,
chr21:30070984-30073381~~chr21:30257090-30259197,
chr21:30071470-30073906~~chr21:30257148-30259258,
chr21:30071517-30073936~~chr21:30193737-30195757,
chr21:30071583-30074009~~chr21:30193870-30195773,
chr21:30071597-30073842~~chr21:30194040-30195598,
chr21:30071597-30073842~~chr21:30257103-30259279,
chr21:30071749-30073856~~chr21:30194075-30195765,
chr21:30071750-30073955~~chr21:30193790-30195799,
chr21:30071764-30073904~~chr21:30256697-30259212,
chr21:30071764-30073904~~chr21:30732343-30733854,
chr21:30071825-30073458~~chr21:30194117-30195675,
chr21:30071865-30073462~~chr21:30193877-30195720,
chr21:30071886-30073585~~chr21:30194049-30195711,
chr21:30075000-30100000~~chr21:30175000-30200000,
chr21:30075000-30100000~~chr21:30250000-30275000,
chr21:30075000-30100000~~chr21:30925000-30950000,