- Basic information
- CohesinDB ID: CDBP00416346
- Locus: chr21-30146589-30147268
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Data sourse: GSE101921, GSE131606
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Cell type: HMEC, MCF-10A, DKO
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Rad21,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
24% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 80%,
"9_Het": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, ZNF660, FOXA1, TP63, MAF, KLF5, TEAD1, ETV1, SNAI2, ESR1, JUN, EP300, BAF155, GATA6, SOX4, E2F1, TEAD4, TFAP2C, NANOG, CHD8, BRD3, ID3, ZNF317, ZBTB17, ERG, ZBTB21, ASCL1, MYC, GABPA, STAT3, NKX3-1, RCOR1, ARNTL, ZNF750, ESRRA, CEBPB, NR3C1, CREB1, FEZF1, GRHL2, TRPS1, EHF, GATA2, FLI1, SMC1A, SMAD3, SMARCC1, PRDM10, CREBBP, RUNX2, GR, SP3, NRF1, PBX4, ARNT, FOS, PIAS1, NR1H2, REST, ARID1A, ASH2L, SMC3, ELL2, STAG2, FOXA2, HOXB13, KDM1A, YY1, RELA, JUNB, ISL1, HIF1A, GATA3, MAX, NRIP1, KLF4, TCF7L2, KDM5B, TP53, NFKB1, PHOX2B, BRD2, AR, YAP1, EGLN2, ZBTB42, BRD4, BRCA1, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: Stroke
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops