- Basic information
- CohesinDB ID: CDBP00416352
- Locus: chr21-30215371-30216094
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Data sourse: GSE116868, GSE67783, GSE86191
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Cell type: HCT-116, HSPC, MB157
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
24% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 79%,
"7_Enh": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, POU2F2, CHD8, PGR, FOXA2, NANOG, ZFX, MEIS2, XBP1, SMAD3, ZSCAN5A, DUX4, FOXA1, HOXB13, HNF4G, ERG, TFAP4, RELA, NEUROD1, EZH1, MYC, BRG1, ONECUT1, GR, GRHL3, HIF1A, ARNT, NRF1, OTX2, GATA3, NKX2-1, GABPA, STAT3, NKX3-1, ZNF143, RCOR1, HDAC3, ARNTL, TLE3, ZNF750, NR3C1, ESRRA, TEAD1, SCRT2, ETV1, PIAS1, EZH2, KDM5B, ESR1, CREB1, MED26, GRHL2, SETDB1, TRPS1, BAF155, EP300, SP1, AR, PAX3-FOXO1, GATA2, ARID1A, EGLN2, ASH2L, NOTCH3, BRD4, SCRT1, FOXP1, CLOCK, SMC3, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): GRIK1
- Function elements
- Human SNPs: Urate_levels
- Number of somatic mutations (coding): 148
- Number of somatic mutations (non-coding): 148
- Related genes and loops