- Basic information
- CohesinDB ID: CDBP00416361
- Locus: chr21-30268566-30269045
-
Data sourse: ENCSR000BLD, GSE93080, GSE143937, ENCSR000BKV, GSE138405, GSE25021, ENCSR000BLY, GSE105028, ENCSR000ECE, GSE55407, ENCSR000EHX, GSE103477, GSE111537, GSE106870, GSE50893, GSE145327, GSE97394, GSE131577
-
Cell type: MCF-7, GM2630, H1-hESC, Hela-Kyoto, HL-60, GM2610, CVB-hiPSC, GM12878, GM2588, HUES64, GM19238, SK-N-SH, K-562, OCI-AML-3, THP-1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 7% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.822
- Subunit: SA1,Rad21,SA2,SMC1
-
CTCF binding site: CTCF
CTCF motif: True
- Genomic location: TSS,Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
22% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 90%,
"9_Het": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: NANOG, SMC1A, PGR, POU2F2, CHD8, SOX2, TEAD4, STAG2, ZFX, GTF2B, SMAD3, STAT1, FOXA1, SRF, ZNF654, MEF2C, ERG, YY1, RELA, ZBTB2, MYC, SMARCA4, RAD21, PRDM1, GRHL3, HIF1A, GABPA, SPIB, ZNF143, SFPQ, MED1, CEBPB, TRIM28, MYB, RBM39, ESR1, SETDB1, CTCF, SPI1, LMO1, AR, REST, GATA2, HSF1, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): GRIK1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 8
- Related genes and loops
- Related gene:
ENSG00000171189,
- Related loop:
chr21:29925000-29950000~~chr21:30250000-30275000,
chr21:30025000-30050000~~chr21:30250000-30275000,
chr21:30075000-30100000~~chr21:30250000-30275000,
chr21:30150000-30175000~~chr21:30250000-30275000,
chr21:30250000-30275000~~chr21:30400000-30425000,
chr21:30250000-30275000~~chr21:30500000-30525000,
chr21:30250000-30275000~~chr21:31050000-31075000,
chr21:30268150-30269592~~chr21:31085537-31087555,
chr21:30268178-30269643~~chr21:30408195-30409710,