- Basic information
- CohesinDB ID: CDBP00416381
- Locus: chr21-30433796-30434520
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR000EGW, ENCSR000BLY, GSE105028, GSE121355, GSE103477, GSE111537, GSE131606, GSE108869, ENCSR000EDW, GSE25021, ENCSR917QNE, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE143937, ENCSR000BKV, GSE115250, GSE138405, GSE86191, GSE76893, GSE101921, GSE112028, GSE130135, ENCSR703TNG, GSE106870, GSE116344, GSE138105, GSE145327, GSE94872, ENCSR000EEG, ENCSR338DUC, ENCSR193NSH, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, GSE85526, ENCSR000ECE, GSE206145, ENCSR000BMY, ENCSR000EHX, ENCSR620NWG, ENCSR984DZW, GSE97394, GSE55407, ENCSR000BTQ, GSE105004, ENCSR167MTG, ENCSR956LGB, GSE131956, GSE110061, GSE129526, GSE111913, GSE155324, GSE38411, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS, GSE131577
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Cell type: MDM, RH4, GM2610, SLK, CVB-hiPSC, GM19240, Liver, TC-32, HuCC-T1, H9-hESC, GM2630, HMEC, HEKn, Ishikawa, GM12890, HeLa-S3, GM2255, BCBL-1, K-562, GM18486, DKO, H1-hESC, SNYDER, GM18505, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, HeLa-Tet-On, RT-112, THP-1, HUES64, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, A-549, HUVEC, GM19238, HeLa, CNCC-WT33iPSC, TC-71, OCI-AML-3
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 31% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.444
- Subunit: SA1,Rad21,SMC1,SMC3ac,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
22% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 83%,
"14_ReprPCWk": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, SMC1A, CHD8, NKX2-2, MYCN, ZNF660, CREM, TEAD4, STAG2, POU4F2, XBP1, SMAD3, DUX4, FOXA1, SRF, ZNF654, HOXB13, ERG, KDM1A, RELA, ZNF35, MYC, RUNX2, RAD21, ARNT, HIF1A, GRHL3, NKX2-1, OTX2, PRDM9, GABPA, MAX, GATA1, ZNF143, MITF, NFE2, ARNTL, TEAD3, TEAD1, TRIM28, CREB1, SMAD1, KDM5B, ESR1, TP53, MED26, SETDB1, MYOD1, CTCF, USF1, EP300, BCL11A, ZNF695, HNF4A, BHLHE40, AR, PAX3-FOXO1, RYBP, SOX4, REST, E2F6, EGLN2, HSF1, BRD4, JUND, TCF3, FOXP1, E2F1, SMC1, MRTFB, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 8
- Related genes and loops
- Related gene:
- Related loop:
chr21:29375000-29400000~~chr21:30425000-30450000,
chr21:30043654-30045703~~chr21:30433235-30435097,
chr21:30043774-30045603~~chr21:30433524-30435077,
chr21:30325000-30350000~~chr21:30425000-30450000,
chr21:30340030-30342152~~chr21:30433551-30435071,
chr21:30340048-30341945~~chr21:30433610-30434852,
chr21:30340360-30341986~~chr21:30433572-30435022,
chr21:30344537-30345918~~chr21:30433207-30435071,
chr21:30425000-30450000~~chr21:31075000-31100000,
chr21:30425000-30450000~~chr21:31600000-31625000,
chr21:30433599-30434839~~chr21:31085880-31087834,