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Basic information

CohesinDB ID: CDBP00416394

Locus: chr21-30505571-30506784

Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR000BLY, GSE105028, GSE121355, GSE131606, GSE25021, ENCSR917QNE, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, ENCSR000BKV, GSE138405, GSE76893, GSE101921, GSE112028, GSE130135, ENCSR703TNG, GSE106870, GSE145327, ENCSR000EEG, ENCSR000BLS, ENCSR000EHW, GSE85526, ENCSR000ECE, GSE206145, ENCSR000BMY, ENCSR000EHX, GSE97394, ENCSR000BTQ, GSE110061, GSE129526, ENCSR000EDE, GSE68388, GSE126990, GSE50893, ENCSR000ECS, GSE131577

Cell type: GM2610, CVI-hiPSC, Liver, HuCC-T1, H9-hESC, GM2630, HMEC, HEKn, Ishikawa, GM12890, HeLa-S3, K-562, GM18486, DKO, H1-hESC, SNYDER, GM12878, GM12891, GM2588, SK-N-SH, HeLa-Tet-On, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, GM19238, CNCC-WT33iPSC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 19% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.633

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 19% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 98%, "9_Het": 2%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: SMC1A, TOP2A, CDK7, SMAD3, FOXA1, SIRT3, SRF, TRIM22, HOXB13, ERG, HOXC5, RELA, MYC, CTCFL, RAD21, ARNT, GRHL3, HIF1A, GATA3, GABPA, STAT3, NKX3-1, ZNF143, ZEB1, TEAD1, PIAS1, STAG1, KDM5B, ESR1, CTCF, BAF155, AR, IRF4, BRD4, CLOCK, SMC1, SMC3, STAG2

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 15

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00416394