- Basic information
- CohesinDB ID: CDBP00416445
- Locus: chr21-30935140-30937124
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Data sourse: GSE118494, GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015
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Cell type: RPE, Fibroblast, HCT-116, IMR-90, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
21% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 58%,
"9_Het": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, POU2F2, SMC1A, ZNF283, FOXA2, ZSCAN5D, EBF1, POU5F1, KDM4C, ZFX, CRY1, XBP1, ZNF263, WT1, ZBTB48, POU4F2, TBL1X, ZSCAN5A, TET2, MYCN, YY1, RELA, OGG1, ATF3, MYC, SP140, GRHL3, HIF1A, PRDM9, STAT3, MAF1, TP63, ZNF143, DNMT3B, MED1, KDM6B, TRIM28, EZH2, GRHL2, SETDB1, MYOD1, CTCF, ARRB1, GSPT2, AR, HEXIM1, HSF1, RAD51, NOTCH3, BRD4, CLOCK, MAZ, HCFC1R1, AATF, SMC3, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 12
- Related genes and loops