- Basic information
- CohesinDB ID: CDBP00416465
- Locus: chr21-31106786-31110561
-
Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR000BSB, GSE126634, ENCSR000BLY, GSE105028, GSE103477, GSE111537, GSE131606, GSE108869, GSE25021, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE139435, ENCSR000DZP, ENCSR000EAC, GSE67783, GSE86191, GSE93080, GSE138405, GSE76893, GSE101921, GSE135093, GSE152721, GSE120943, ENCSR198ZYJ, GSE206145-NatGen2015, GSE130135, ENCSR703TNG, GSE106870, GSE116344, GSE145327, GSE94872, ENCSR895JMI, ENCSR000EEG, GSE130140, GSE76815, GSE98367, ENCSR000BLS, ENCSR000EHW, GSE206145, ENCSR000ECE, GSE62063, ENCSR000BMY, ENCSR000EHX, ENCSR984DZW, GSE97394, ENCSR217ELF, ENCSR000BTQ, GSE55407, ENCSR167MTG, ENCSR853VWZ, GSE131956, GSE129526, ENCSR000HPG, GSE155324, GSE38411, ENCSR054FKH, ENCSR000EDE, GSE68388, GSE126990, GSE50893, ENCSR748MVX, GSE131577
-
Cell type: MDM, RH4, GM10847, GM2610, CVB-hiPSC, GM19240, HSPC, CUTLL1, CVI-hiPSC, Liver, HuCC-T1, B-cell, H9-hESC, GM2630, HMEC, Fibroblast, RPE, THP-1, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, BCBL-1, GM18486, DKO, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, Leukemia-SEM, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, HAP1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, A-549, HUVEC, Ramos, GM19238, OCI-AML-3, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 36% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.344
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
-
CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
54% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 42%,
"7_Enh": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: TRIM28, ZNF585B
- Target gene symbol (double-evidenced CRMs): MIS18A,TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 29
- Related genes and loops
- Related gene:
ENSG00000156299,
ENSG00000159055,
- Related loop:
chr21:31100000-31125000~~chr21:31575000-31600000,
chr21:31100000-31125000~~chr21:31600000-31625000,
chr21:31100000-31125000~~chr21:32250000-32275000,
chr21:31100000-31125000~~chr21:32800000-32825000,
chr21:31108225-31109947~~chr21:31603740-31605904,
chr21:31108228-31109954~~chr21:31141372-31143715,
chr21:31108228-31109954~~chr21:31179697-31181922,
chr21:31108237-31110143~~chr21:31179749-31181978,
chr21:31108237-31110143~~chr21:31579669-31582192,
chr21:31108247-31110001~~chr21:31142031-31143645,
chr21:31108247-31110001~~chr21:31179767-31181764,
chr21:31108247-31110001~~chr21:31579897-31582091,
chr21:31108247-31110001~~chr21:31603560-31606026,
chr21:31108253-31109958~~chr21:31179725-31181960,
chr21:31108253-31109964~~chr21:31179752-31181752,
chr21:31108255-31109956~~chr21:31179733-31181943,
chr21:31108264-31109975~~chr21:31142192-31143682,
chr21:31108300-31109854~~chr21:31579888-31581990,
chr21:31108302-31109934~~chr21:31603591-31605976,
chr21:31108349-31109945~~chr21:31603460-31605984,
chr21:31108353-31109891~~chr21:31179855-31181435,
chr21:31108376-31109926~~chr21:31603651-31605924,
chr21:31108400-31109986~~chr21:31612358-31613962,
chr21:31108420-31109889~~chr21:31603648-31605747,
chr21:31108511-31109905~~chr21:31179984-31181987,