Deatailed information for cohesin site CDBP00416471


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  • Basic information
  • CohesinDB ID: CDBP00416471
  • Locus: chr21-31125565-31125905
  • Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191
  • Cell type: Fibroblast, HCT-116, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.967
  • Subunit: SA1,Rad21
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 54% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 54%, "15_Quies": 26%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: RUNX1, PAX7, NANOG, SMC1A, CBFA2T2, CEBPA, POU2F2, BRD1, RUNX1T1, SOX2, ZFX, BCL6, XBP1, MYCN, SMAD3, ZSCAN5A, ZBTB48, STAT1, WT1, FOXA1, MEF2C, ERG3, CDK9, ERG, YY1, RELA, ZNF384, MYC, SMAD2, EOMES, CHD7, PRDM1, GRHL3, RAD21, SP140, RXRA, OTX2, ARNT, GABPA, SMAD4, MAX, PAX5, SPIB, ZNF143, CDK8, TERF2, CEBPB, TERF1, TRIM28, MYB, SCRT2, EZH2, CHD8, ESR1, TP53, ZNF334, JUN, TCF12, CTCF, SPI1, BCL11A, PSIP1, NFATC1, AR, T, FOXA2, RXR, GATA2, TRIM24, SIX2, FLI1, NOTCH3, BRD4, CLOCK, MAZ, SMC3
  • Target gene symbol (double-evidenced CRMs): MIS18A,TIAM1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 6
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops

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