- Basic information
- CohesinDB ID: CDBP00416473
- Locus: chr21-31136782-31137273
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Data sourse: ENCSR000EAC, ENCSR000BKV, ENCSR000FAD, GSE86191, ENCSR000BLY, ENCSR000EHW, ENCSR000EHX, GSE50893, GSE38411
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Cell type: GM12892, HCT-116, GM2610, GM12878, GM2588, K-562, SK-N-SH, BCBL-1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SMC3,Rad21,SA1,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
54% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 39%,
"15_Quies": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, NANOG, MEF2B, SMC1A, CEBPA, POU5F1, EBF1, MYCN, BCL6, ZFX, CHD2, ZNF44, FOXA1, SRF, ZNF563, TRIM22, HOXB13, KDM1A, YY1, ERG, ZBTB2, PBX1, ATF3, MYC, NFIC, OSR2, RUNX3, FOXP2, RAD21, HIF1A, SKIL, ATF4, GATA3, TAL1, MAX, PAX5, NKX3-1, GATA1, IKZF1, ZNF143, CDK8, HAND2, MED1, ARNTL, CBX2, NR3C1, JMJD1C, CEBPB, ZNF667, KMT2A, MYB, PIAS1, EZH2, MED, EBF3, CTCF, SND1, TCF12, SPI1, SP1, TBX21, BHLHE40, BCL11A, AR, BAF155, GATA2, GATAD2B, TRIM24, FLI1, BRD4, TCF3, FOXP1, ZNF766, RELB, MAZ, MRTFB, SMC3, ZNF554, E2F1, ZNF490, RBPJ
- Target gene symbol (double-evidenced CRMs): TIAM1,MIS18A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 15
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156299,
ENSG00000159055,
- Related loop:
chr21:31097524-31100200~~chr21:31142192-31143682,
chr21:31097659-31100122~~chr21:31142126-31143686,
chr21:31097834-31100105~~chr21:31142031-31143645,
chr21:31097840-31099933~~chr21:31142156-31143409,
chr21:31097896-31099782~~chr21:31142212-31143628,
chr21:31108228-31109954~~chr21:31141372-31143715,
chr21:31108247-31110001~~chr21:31142031-31143645,
chr21:31108264-31109975~~chr21:31142192-31143682,
chr21:31125000-31150000~~chr21:31250000-31275000,
chr21:31125000-31150000~~chr21:31575000-31600000,
chr21:31125000-31150000~~chr21:32275000-32300000,