- Basic information
- CohesinDB ID: CDBP00416478
- Locus: chr21-31146265-31147154
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Data sourse: ENCSR000BLD, GSE206145-NatGen2015, GSE67783, ENCSR153HNT
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Cell type: K-562, H1-hESC, Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
54% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 43%,
"15_Quies": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF496, POU5F1, TOP2A, ZFX, XBP1, GTF2B, ZSCAN16, ERG3, ERG, ZNF384, RUNX2, SP140, GRHL3, PRDM1, ARNT, GATA3, PRDM9, GABPA, PAX5, MED1, ZNF780A, ELF1, TRIM28, ZNF22, TBX21, LMO1, AR, GATA2, BRD4, AHR
- Target gene symbol (double-evidenced CRMs): TIAM1,MIS18A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 117
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156299,
ENSG00000159055,
- Related loop:
chr21:29275000-29300000~~chr21:31150000-31175000,
chr21:30675000-30700000~~chr21:31150000-31175000,
chr21:31000000-31025000~~chr21:31150000-31175000,
chr21:31097524-31100200~~chr21:31142192-31143682,
chr21:31097659-31100122~~chr21:31142126-31143686,
chr21:31097834-31100105~~chr21:31142031-31143645,
chr21:31097840-31099933~~chr21:31142156-31143409,
chr21:31097896-31099782~~chr21:31142212-31143628,
chr21:31108228-31109954~~chr21:31141372-31143715,
chr21:31108247-31110001~~chr21:31142031-31143645,
chr21:31108264-31109975~~chr21:31142192-31143682,
chr21:31125000-31150000~~chr21:31250000-31275000,
chr21:31125000-31150000~~chr21:31575000-31600000,
chr21:31125000-31150000~~chr21:32275000-32300000,
chr21:31150000-31175000~~chr21:31250000-31275000,
chr21:31150000-31175000~~chr21:31375000-31400000,
chr21:31150000-31175000~~chr21:31575000-31600000,
chr21:31150000-31175000~~chr21:32250000-32275000,