- Basic information
- CohesinDB ID: CDBP00416479
- Locus: chr21-31151663-31152151
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Data sourse: ENCSR000EHW, ENCSR230ZWH, ENCSR000EHX, ENCSR000BLY
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Cell type: Liver, SK-N-SH
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC3,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
54% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 38%,
"5_TxWk": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, MEF2B, CHD8, FOXA2, NKX2-2, EBF1, CEBPA, PAF1, CHD2, ZNF600, MTA2, MYCN, ERF, KDM4C, XBP1, FOXA1, HOXB13, ERG, KDM1A, RELA, ISL1, RAD21, ARNT, CHD7, GATA3, GABPA, ZNF8, PBX3, NKX3-1, GATA1, ZNF143, RCOR1, TERF2, HAND2, MED1, JMJD1C, NR2F2, TRIM28, SCRT2, EZH2, OCA2, PITX3, EBF3, PHOX2B, TCF12, EP300, SP1, TBX21, SPI1, AR, BAF155, GATA2, REST, IRF4, ZNF146, FLI1, ASH2L, MXI1, BRD4, MRTFB, TEAD4, TBX2, PDX1
- Target gene symbol (double-evidenced CRMs): BACH1,TIAM1,MIS18A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 12
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156273,
ENSG00000156299,
ENSG00000159055,
- Related loop:
chr21:29275000-29300000~~chr21:31150000-31175000,
chr21:30675000-30700000~~chr21:31150000-31175000,
chr21:31000000-31025000~~chr21:31150000-31175000,
chr21:31125000-31150000~~chr21:31250000-31275000,
chr21:31125000-31150000~~chr21:31575000-31600000,
chr21:31125000-31150000~~chr21:32275000-32300000,
chr21:31150000-31175000~~chr21:31250000-31275000,
chr21:31150000-31175000~~chr21:31375000-31400000,
chr21:31150000-31175000~~chr21:31575000-31600000,
chr21:31150000-31175000~~chr21:32250000-32275000,