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Basic information

CohesinDB ID: CDBP00416486

Locus: chr21-31172023-31172627

Data sourse: GSE98367, ENCSR000EHX, ENCSR917QNE

Cell type: Liver, Macrophage, SK-N-SH

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 54% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 41%, "5_TxWk": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CHD8, MYCN, CHD2, PAF1, ZFX, POU4F2, XBP1, ZBTB17, ZSCAN5A, TBP, RELA, RARA, ONECUT1, EZH1, SMARCA4, HIF1A, NKX2-1, SMARCE1, XRCC5, CDK8, HAND2, KLF5, ZNF331, EZH2, KDM5B, TP53, ESR1, PITX3, GRHL2, JUN, CTCF, USF1, AR, GATA2, REST, RFX5, MXI1, BRD4, STAG1

Target gene symbol (double-evidenced CRMs): MIS18A,TIAM1,BACH1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 24

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000156273, ENSG00000156299, ENSG00000159055,

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Deatailed information for cohesin site CDBP00416486