- Basic information
- CohesinDB ID: CDBP00416489
- Locus: chr21-31177211-31177721
-
Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191, GSE98367
-
Cell type: Fibroblast, HCT-116, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
54% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 39%,
"5_TxWk": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, POU2F2, BCL6, PGR, CEBPA, MYCN, SMC1A, CHD2, PAF1, TOP2A, ZFX, ZBTB48, WT1, STAT1, FOXA1, DDX5, CDK9, ZNF300, KDM1A, ZNF19, ERG, RELA, ZNF384, ZNF341, EOMES, RAD21, ARNT, GRHL3, GATA3, TAL1, PBX3, GATA1, IKZF1, RCOR1, HAND2, VDR, JMJD1C, CEBPB, MAF, TRIM28, KMT2A, SCRT2, TCF7L2, MYB, EZH2, LMO2, ESR1, MLL, PITX3, EBF3, CTCF, TCF12, EP300, SPI1, BCL11A, NR4A1, AR, PAX3-FOXO1, GATA6, ZBTB16, NKX2-5, GATA2, RBM25, MAML3, BRD4, SCRT1
- Target gene symbol (double-evidenced CRMs): MIS18A,CFAP298-TCP10L,CFAP298,TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156299,
ENSG00000159055,
ENSG00000265590,
ENSG00000159079,
- Related loop:
chr21:29075000-29100000~~chr21:31175000-31200000,
chr21:29275000-29300000~~chr21:31150000-31175000,
chr21:30257134-30259115~~chr21:31179827-31181941,
chr21:30675000-30700000~~chr21:31150000-31175000,
chr21:31000000-31025000~~chr21:31150000-31175000,
chr21:31075000-31100000~~chr21:31175000-31200000,
chr21:31097524-31100200~~chr21:31179837-31181523,
chr21:31097635-31100206~~chr21:31179733-31181943,
chr21:31097651-31099664~~chr21:31180070-31181408,
chr21:31097659-31100122~~chr21:31179749-31181978,
chr21:31097665-31099883~~chr21:31179820-31181485,
chr21:31097675-31100213~~chr21:31179786-31181766,
chr21:31097685-31100223~~chr21:31179725-31181960,
chr21:31097698-31099915~~chr21:31179762-31181496,
chr21:31097825-31099965~~chr21:31179895-31181473,
chr21:31097828-31099837~~chr21:31179837-31181676,
chr21:31097834-31100105~~chr21:31179767-31181764,
chr21:31097840-31099913~~chr21:31179591-31181602,
chr21:31097840-31099933~~chr21:31179984-31181987,
chr21:31097840-31099938~~chr21:31179884-31181375,
chr21:31097847-31099741~~chr21:31179752-31181752,
chr21:31097852-31099834~~chr21:31179993-31181603,
chr21:31097853-31099955~~chr21:31179971-31181817,
chr21:31097866-31100218~~chr21:31179704-31181750,
chr21:31097877-31099898~~chr21:31179824-31181444,
chr21:31097883-31100039~~chr21:31179697-31181922,
chr21:31097887-31099829~~chr21:31179855-31181435,
chr21:31097887-31099865~~chr21:31179702-31181755,
chr21:31097887-31099870~~chr21:31179832-31181897,
chr21:31097892-31099900~~chr21:31179769-31181792,
chr21:31097893-31100303~~chr21:31179706-31181949,
chr21:31097896-31099782~~chr21:31179835-31181470,
chr21:31097906-31099678~~chr21:31180055-31181588,
chr21:31097906-31100239~~chr21:31179824-31181763,
chr21:31097923-31099913~~chr21:31179767-31181689,
chr21:31097941-31100177~~chr21:31179879-31181642,
chr21:31097943-31100132~~chr21:31179993-31181674,
chr21:31097962-31099613~~chr21:31180019-31181392,
chr21:31097968-31099503~~chr21:31179934-31181426,
chr21:31097976-31099983~~chr21:31179818-31181407,
chr21:31097982-31099419~~chr21:31179870-31181422,
chr21:31097986-31099396~~chr21:31180102-31181374,
chr21:31098023-31099887~~chr21:31180055-31181418,
chr21:31108228-31109954~~chr21:31179697-31181922,
chr21:31108237-31110143~~chr21:31179749-31181978,
chr21:31108247-31110001~~chr21:31179767-31181764,
chr21:31108253-31109958~~chr21:31179725-31181960,
chr21:31108253-31109964~~chr21:31179752-31181752,
chr21:31108255-31109956~~chr21:31179733-31181943,
chr21:31108353-31109891~~chr21:31179855-31181435,
chr21:31108511-31109905~~chr21:31179984-31181987,
chr21:31150000-31175000~~chr21:31250000-31275000,
chr21:31150000-31175000~~chr21:31375000-31400000,
chr21:31150000-31175000~~chr21:31575000-31600000,
chr21:31150000-31175000~~chr21:32250000-32275000,
chr21:31175000-31200000~~chr21:31325000-31350000,
chr21:31175000-31200000~~chr21:31400000-31425000,
chr21:31175000-31200000~~chr21:31450000-31475000,
chr21:31175000-31200000~~chr21:31500000-31525000,
chr21:31175000-31200000~~chr21:31550000-31575000,
chr21:31175000-31200000~~chr21:31575000-31600000,
chr21:31175000-31200000~~chr21:31600000-31625000,
chr21:31175000-31200000~~chr21:32250000-32275000,
chr21:31175000-31200000~~chr21:32575000-32600000,
chr21:31179704-31181750~~chr21:31603484-31605864,
chr21:31179749-31181978~~chr21:31579669-31582192,
chr21:31179749-31181978~~chr21:31603531-31606025,
chr21:31179770-31181885~~chr21:31603563-31605907,
chr21:31179837-31181523~~chr21:31580135-31582040,
chr21:31179884-31181375~~chr21:31579988-31582000,