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Basic information

CohesinDB ID: CDBP00416505

Locus: chr21-31227985-31228256

Data sourse: GSE206145, GSE206145-NatGen2015, GSE206145-GSE177045

Cell type: MCF-7, Fibroblast, RPE

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Mau2,SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 54% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 56%, "5_TxWk": 42%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFATC3, POU2F2, ZSCAN5C, TOP2A, DUX4, FOXA1, ZNF384, ZNF362, SP140, ARNT, NKX2-1, PAX5, ZNF143, IKZF1, EZH2, LMO2, NFKB1, ZNF22, CTCF, IRF1, ZNF146, IKZF2, CLOCK, ZNF490

Target gene symbol (double-evidenced CRMs): TIAM1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 2

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000156299,

eachgene

Deatailed information for cohesin site CDBP00416505