- Basic information
- CohesinDB ID: CDBP00416508
- Locus: chr21-31235816-31236997
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Data sourse: GSE206145-GSE177045, GSE72082, GSE206145, GSE206145-NatGen2015, ENCSR703TNG, GSE25021, GSE115602
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Cell type: MCF-7, Fibroblast, RPE
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
54% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 48%,
"5_TxWk": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, PGR, XBP1, FOXA1, MLL4, TFAP4, THAP1, CHD7, SMARCE1, PAX5, MITF, ZNF506, TEAD1, ELF1, TRIM28, LMO2, ESR1, TP73, ZNF561, ZNF577, CTCF, TCF12, EP300, BAF155, JUN, LMO1, GATA6, DPF2, TRIM24, E2F1, NR5A2, TEAD4, ZNF92, TFAP2C, GLIS1, CHD8, ZSCAN5D, POU5F1, MYCN, TOP2A, RUNX1T1, ERG, MYC, SMARCA4, RXRA, PROX1, GABPA, STAT3, IKZF1, RCOR1, ARNTL, NR3C1, CEBPB, ESRRA, ZNF750, STAT5B, KMT2A, GRHL2, TRPS1, SPI1, HDAC2, GATA2, NCOA2, ZNF554, RUNX1, SMC1A, CEBPA, NKX2-2, SIN3A, ZFX, POU4F2, SMAD3, CREBBP, ZXDC, ZNF133, RUNX2, GATA4, GR, PBX4, DAXX, NFIB, ARNT, SMAD4, FOXM1, CDK8, MED1, MYB, PIAS1, C11orf30, NIPBL, TFAP2A, HNF4A, CTBP2, PHIP, FOXP1, FOXA2, SS18, ZNF574, CDK9, HOXB13, RELA, BRG1, ZIC2, HIF1A, GATA3, TAL1, MAX, NRIP1, HAND2, TLE3, NR2F2, TCF7L2, NR2F1, TP53, ZNF334, PHOX2B, ELF3, ZFP28, PAX3-FOXO1, AR, YAP1, EGLN2, BRD4, JUND, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 14
- Number of somatic mutations (non-coding): 0
- Related genes and loops