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Basic information

CohesinDB ID: CDBP00416509

Locus: chr21-31248699-31249077

Data sourse: GSE206145, GSE101921, GSE206145-NatGen2015, GSE68388

Cell type: RPE, HMEC, Fibroblast, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 54% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 44%, "5_TxWk": 42%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, PGR, SMC1A, CHD8, FOXA2, NKX2-2, ZNF316, ZSCAN5D, POU2F2, ZFX, ZNF317, XBP1, SMAD3, MAFF, FOXA1, HOXB13, ERG, RELA, CREBBP, JUNB, ATF3, RUNX2, GR, RAD21, PBX4, HIF1A, GATA3, SMARCE1, MAX, FOS, ZNF143, RCOR1, MITF, MED1, VDR, PLAG1, NR3C1, ESRRA, ZNF750, KLF4, TEAD1, CEBPB, SNAI2, LMO2, TP53, ZBTB6, C11orf30, MYOD1, BRD2, JUN, CTCF, MAFK, USF1, SPI1, AR, PAX3-FOXO1, GATA2, YAP1, FLI1, ZNF548, BRD4, SCRT1, E2F1, TEAD4, STAG2, TFAP2C, FOSL2

Target gene symbol (double-evidenced CRMs): TIAM1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 2

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000156299,

eachgene

Deatailed information for cohesin site CDBP00416509