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Basic information

CohesinDB ID: CDBP00416511

Locus: chr21-31251638-31252437

Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783, GSE86191

Cell type: RPE, Fibroblast, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 59% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 39%, "15_Quies": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, TRP47, CBFA2T2, CDK9-HEXIM1, AGO1, MYCN, POU5F1, FOXA2, HMGN3, ZFX, NME2, XBP1, SOX2, ZBTB48, ZSCAN5A, WT1, STAT1, TEAD4, ERG, YY1, RELA, KDM1A, OGG1, ATF3, MYC, ZBTB5, ISL1, SP140, GRHL3, HIF1A, CBFB, GABPA, DPF1, STAT3, NCAPH2, TP63, PRDM14, HAND2, PLAG1, KDM6B, NR2F1, EZH2, ESR1, ZNF334, SETDB1, USF2, EBF3, GABPB1, CTCF, PHOX2B, USF1, SPI1, GSPT2, AR, RXR, HEXIM1, FLI1, HSF1, TFIIIC, RAD51, BRD4, NOTCH3, MAZ, AATF, SMC3, TBX2, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): GRIK1,SCAF4,TIAM1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 330

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000171189, ENSG00000156299, ENSG00000156304,

eachgene

Deatailed information for cohesin site CDBP00416511