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Basic information

CohesinDB ID: CDBP00416512

Locus: chr21-31256576-31256637

Data sourse: GSE120943, GSE98367

Cell type: Monocytes, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 59% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 54%, "5_TxWk": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXA2, ZNF263, MYCN, KDM4C, ZFX, ZSCAN16, DUX4, FOXA1, ERG3, DDX5, ERG2, HOXB13, ZFHX2, YY1, RELA, JUNB, RUNX2, SMARCA4, SP140, PRDM9, STAT3, TAL1, ZSCAN4, MAX, FOS, RCOR1, MED1, CEBPB, TEAD1, EZH2, OCA2, ZNF334, EGR2, CTCF, AR, GATA2, NOTCH3, BRD4, TEAD4, STAG1

Target gene symbol (double-evidenced CRMs): GRIK1,TIAM1,SCAF4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 4

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000171189, ENSG00000156299, ENSG00000156304,

eachgene

Deatailed information for cohesin site CDBP00416512