- Basic information
- CohesinDB ID: CDBP00416513
- Locus: chr21-31257732-31258158
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783
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Cell type: RPE, Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 51%,
"5_TxWk": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXA2, ZNF263, MYCN, KDM4C, ZFX, ZSCAN16, DUX4, FOXA1, ERG3, DDX5, ERG2, HOXB13, ZFHX2, YY1, RELA, JUNB, RUNX2, SMARCA4, SP140, PRDM9, STAT3, TAL1, ZSCAN4, MAX, FOS, RCOR1, MED1, CEBPB, TEAD1, EZH2, OCA2, ZNF334, EGR2, CTCF, AR, GATA2, NOTCH3, BRD4, TEAD4, STAG1
- Target gene symbol (double-evidenced CRMs): GRIK1,SCAF4,TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 8
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000171189,
ENSG00000156299,
ENSG00000156304,
- Related loop:
chr21:29175000-29200000~~chr21:31250000-31275000,
chr21:29675000-29700000~~chr21:31250000-31275000,
chr21:29800000-29825000~~chr21:31250000-31275000,
chr21:30675000-30700000~~chr21:31250000-31275000,
chr21:30825000-30850000~~chr21:31250000-31275000,
chr21:30875000-30900000~~chr21:31250000-31275000,
chr21:31125000-31150000~~chr21:31250000-31275000,
chr21:31150000-31175000~~chr21:31250000-31275000,
chr21:31250000-31275000~~chr21:31375000-31400000,
chr21:31250000-31275000~~chr21:31400000-31425000,
chr21:31250000-31275000~~chr21:31475000-31500000,
chr21:31250000-31275000~~chr21:31500000-31525000,
chr21:31250000-31275000~~chr21:31575000-31600000,
chr21:31250000-31275000~~chr21:31600000-31625000,
chr21:31250000-31275000~~chr21:31700000-31725000,
chr21:31250000-31275000~~chr21:31725000-31750000,
chr21:31250000-31275000~~chr21:32225000-32250000,
chr21:31250000-31275000~~chr21:40150000-40175000,