Browse_each

Basic information

CohesinDB ID: CDBP00416514

Locus: chr21-31260562-31261769

Data sourse: GSE67783, GSE98367, GSE206145-NatGen2015, GSE103477, GSE73207

Cell type: MDM, Fibroblast, TF-1, HSPC, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SMC1,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 59% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 58%, "5_TxWk": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RELA, MED1, ZNF384, CHD8, NR2F2, MYC, TOP2A, SIN3A, ZFX, EZH2, XBP1, HIF1A, WT1, ZSCAN5A, ARNT, ERG3, CTCF, SPI1

Target gene symbol (double-evidenced CRMs): TIAM1,GRIK1,SCAF4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 8

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000171189, ENSG00000156299, ENSG00000156304,

eachgene

Deatailed information for cohesin site CDBP00416514