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Basic information

CohesinDB ID: CDBP00416516

Locus: chr21-31265345-31265885

Data sourse: GSE67783, GSE86191, GSE73207

Cell type: TF-1, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 59% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 36%, "5_TxWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXA1, TP63, MITF, TEAD1, ZNF121, TRIM28, ETV1, ESR1, CTCF, BAF155, TRIM24, E2F1, PDX1, POU2F2, NANOG, MYCN, ZNF263, TOP2A, RUNX1T1, POU5F1, ZBTB48, ZSCAN5A, STAT1, DUX4, SRF, DDX5, ERG, PBX1, OGG1, ZNF341, MYC, RAD21, GRHL3, GABPA, APC, STAT3, NKX3-1, PRDM14, KMT2A, EZH2, SPI1, GATA2, FLI1, RUNX1, SMC1A, NKX2-2, ZFX, TET2, ERG3, RUNX2, GATA4, MED1, MYB, PIAS1, ZNF3, REST, ARID1A, FOXP1, SMC3, STAG1, TRP47, TBL1X, FOXA2, PAF1, ZNF600, WT1, HOXB13, KDM1A, YY1, RELA, NEUROD1, BRG1, SP140, HIF1A, OTX2, TAL1, ZNF143, TLE3, NCOA3, TP53, ZNF334, EGR2, BHLHE40, AR, RXR, HSF1, NOTCH3, BRD4, MAZ, AHR

Target gene symbol (double-evidenced CRMs): TIAM1,SCAF4,GRIK1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 4

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000171189, ENSG00000156299, ENSG00000156304,

eachgene

Deatailed information for cohesin site CDBP00416516