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Basic information

CohesinDB ID: CDBP00416519

Locus: chr21-31273209-31273990

Data sourse: ENCSR000BSB, GSE116344, GSE129526, GSE104888

Cell type: RH4, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: NIPBL,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 59% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 57%, "5_TxWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, FOSL1, PGR, SMC1A, FOXA2, CBX3, SOX2, ZFX, XBP1, FOXA1, ERG3, MLL4, ZFHX2, HOXB13, ERG, JUNB, ATF3, RUNX2, ONECUT1, ZFP64, GATA4, RAD21, PRDM1, DAXX, HIF1A, SP140, PROX1, ATF4, STAT3, MAX, PAX5, NKX3-1, FOS, CDK8, NRIP1, TLE3, NR3C1, CEBPB, MYB, KLF6, TCF7L2, PIAS1, TP53, ESR1, FEZF1, SETDB1, EGR2, JUN, CTCF, SPI1, NIPBL, SP1, BHLHE40, BAF155, AR, GATA2, ARID1A, EGR1, ASH2L, ZNF605, BRD4, PHIP, FOXP1

Target gene symbol (double-evidenced CRMs): TIAM1,GRIK1,SCAF4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 4

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000171189, ENSG00000156299, ENSG00000156304,

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Deatailed information for cohesin site CDBP00416519