- Basic information
- CohesinDB ID: CDBP00416524
- Locus: chr21-31284970-31285795
-
Data sourse: GSE67783, GSE86191, GSE129526, GSE206145, GSE206145-NatGen2015, GSE68388, GSE131606
-
Cell type: RPE, Fibroblast, HCT-116, HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 53%,
"7_Enh": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: NFIA, FOSL1, PGR, E2F7, MEIS2, XBP1, PATZ1, FOXA1, PBX2, MLL4, HDGF, ATF3, NFIC, ZC3H8, ZNF362, CHD7, ATF4, ZNF189, SMARCE1, MZF1, ZNF629, KLF5, TEAD1, TRIM28, KLF6, ETV1, LMO2, ESR1, MED26, JUN, TCF12, TAF3, EP300, KLF1, CTCF, MNT, LMO1, GATA6, DPF2, SOX6, E2F1, ZNF528, SMC1, TEAD4, PLRG1, TFAP2C, RBPJ, EED, YBX1, GLIS1, CHD8, POU5F1, BRD3, SRC, MYCN, CTBP1, ZNF317, ZBTB17, MTA2, DUX4, STAT1, ZBTB48, ERG2, ERG, ZBTB21, PBX1, ZNF341, MYC, SMARCA4, TSHZ1, ARID1B, RAD21, ZNF24, GRHL3, RXRA, NKX2-1, FOXK2, PROX1, GABPA, STAT3, APC, XRCC5, IKZF1, RCOR1, NFE2, DACH1, ZNF639, VDR, ARNTL, NR3C1, CEBPB, ESRRA, ZNF750, STAT5B, SPI1, IRF1, KLF17, ZNF257, HDAC2, GATA2, GATAD2B, SIX2, TAF9B, FLI1, MXI1, NCOA2, ZNF554, MYF5, RUNX1, BCL6, HDAC1, EZH2phosphoT487, ZNF707, LDB1, SIN3A, ZFX, SMAD3, ZNF770, ERG3, SMARCC1, TWIST1, ZNF18, PRDM10, CREBBP, ZNF384, RUNX2, SMAD2, GATA4, OSR2, ZNF184, PBX4, DAXX, ARNT, ATF2, HMGB2, ZEB2, ETV6, PBX3, CBFA2T3, FOS, CDK8, SP2, FOXM1, MED1, ZEB1, SPDEF, PML, MYB, ZNF680, SCRT2, SMAD1, ZNF558, HNRNPH1, KLF9, KLF16, MAFK, NIPBL, SP1, BCL11A, NKX2-5, REST, ZBTB7A, ATF7, PHIP, MBD2, FOXP1, SMC3, MLLT1, STAG1, NFATC3, CBFA2T2, CBX3, FOXA2, CREM, EBF1, MEIS1, PAF1, ZNF600, ZNF692, GTF2B, WT1, ESR2, ZBTB33, CDK9, KDM1A, YY1, RELA, JUNB, ZIC2, HIF1A, SKIL, OTX2, GATA3, TAL1, MAX, NRIP1, ZNF143, GATA1, KLF4, ZFP69B, SP7, GFI1B, NR2F2, NCOA3, TCF7L2, NR2F1, KDM5B, TP53, PKNOX1, ZBTB6, ZNF334, NFKB1, MYOD1, ELF3, BRD2, TBX21, BHLHE40, AR, PAX3-FOXO1, YAP1, ZNF366, HSF1, RNF2, NCOR1, BRD4, JUND, MYNN, CLOCK, SCRT1, MAZ, NOTCH3, ZSCAN23, BRCA1, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): TIAM1,EVA1C
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 12
- Number of somatic mutations (non-coding): 0
- Related genes and loops