- Basic information
- CohesinDB ID: CDBP00416535
- Locus: chr21-31312660-31314109
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR000BSB, ENCSR000BLY, GSE105028, GSE121355, GSE25021, GSE131606, ENCSR000EAC, GSE86191, GSE138405, GSE206145-NatGen2015, ENCSR703TNG, GSE94872, GSE206145, GSE85526, ENCSR000ECE, GSE110061, GSE129526, GSE68388, GSE50893
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Cell type: MCF-7, H1-hESC, RPE, Fibroblast, HCT-116, Hela-Kyoto, HEKn, SNYDER, GM12878, HUVEC, GM2588, GM2255, SK-N-SH, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.833
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 70%,
"5_TxWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, SMC1A, FOXA2, NKX2-2, ZFX, ZBTB48, ZNF770, ZBTB44, RAD21, GRHL3, PROX1, OTX2, TAL1, TP63, NKX3-1, CDK8, ZNF750, NR3C1, CEBPB, TCF7L2, EZH2, TP53, CTCF, TCF12, NIPBL, HNF4A, BRD4, PHIP, JUND, TEAD4
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 14
- Number of somatic mutations (non-coding): 0
- Related genes and loops