- Basic information
- CohesinDB ID: CDBP00416537
- Locus: chr21-31316075-31317811
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Data sourse: ENCSR000DZP, GSE104888, GSE67783, GSE86191, ENCSR000BSB, GSE129526, GSE206145-NatGen2015, GSE121355, GSE68388, GSE131606
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Cell type: Fibroblast, HCT-116, GM12878, HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 60%,
"5_TxWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, SOX2, XBP1, FOXA1, MLL4, TFAP4, HDGF, ATF3, CHD7, PRDM1, ZNF273, PAX5, TEAD1, KLF6, ESR1, HNF1B, OCA2, JUN, CTCF, ZNF695, GATA6, TEAD4, TFAP2C, GLIS1, POU2F2, CHD8, BRD1, MTA2, ZNF300, HOXC5, ERG, MYC, SMARCA4, ZKSCAN2, RAD21, GRHL3, PROX1, NKX2-1, GABPA, APC, STAT3, IKZF1, ARNTL, CEBPB, ESRRA, EZH2, GRHL2, EHF, IRF1, FLI1, RELB, ZNF554, RUNX1, CBX1, SMC1A, NKX2-2, SIN3A, ZFX, SMAD3, ZNF770, ERG3, CREBBP, ZNF35, ZNF384, RUNX2, GATA4, DAXX, PBX4, NRF1, ARNT, PRDM9, SMAD4, FOS, CDK8, SCRT2, NIPBL, SP1, HNF4A, ATF7, PHIP, MLLT1, ZNF283, MEF2B, CBX3, FOXA2, PAF1, GTF2B, HOXB13, YY1, RELA, JUNB, HIF1A, GATA3, TAL1, MAX, NRIP1, ZNF143, KLF4, NCOA3, NR2F2, TCF7L2, KDM5B, TP53, NFKB1, ELF3, BRD2, AR, IKZF2, BRD4, JUND, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 16
- Number of somatic mutations (non-coding): 0
- Related genes and loops