- Basic information
- CohesinDB ID: CDBP00416542
- Locus: chr21-31325968-31328155
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Data sourse: GSE93080, GSE206145-GSE177045, ENCSR000EAC, ENCSR000DZP, GSE67783, GSE86191, GSE98367, GSE206145, GSE206145-NatGen2015, GSE120943, GSE50893
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Cell type: MCF-7, GM12892, GM2630, Fibroblast, HCT-116, Macrophage, Monocytes, RPE, SNYDER, GM12878, GM2588, GM19239, HSPC, GM18486, B-cell
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.833
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 39%,
"7_Enh": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, CBX5, XBP1, SUZ12, LEO1, HDGF, ATF3, THAP1, CHD7, RUNX3, PAX5, BACH2, MAF, KLF5, ELF1, TRIM28, BCLAF1, ETV1, TEAD1, LMO2, ZNF217, OCA2, CTCF, TCF12, EP300, ARID5B, LMO1, DPF2, IRF4, RAD51, PDX1, RBPJ, TFAP2C, POU2F2, CHD8, BRD3, POU5F1, TOP2A, RUNX1T1, CDK7, MYCN, MTA2, ZNF317, ZBTB48, ZSCAN5A, STAT1, SRF, NBN, ARID3A, TBP, ERG, PBX1, NFKB2, ETS1, MYC, SMARCA4, RAD21, NKX2-1, GABPA, STAT3, XRCC5, NKX3-1, IKZF1, DNMT3B, KMT2A, EZH2, SPI1, INTS13, GATAD2B, SMARCA5, ZNF766, RELB, RUNX1, BCL6, SMC1A, NKX2-2, CRY1, ZFX, TRIM22, MEF2A, CREBBP, NOTCH1, RUNX2, ARNT, NRF1, ATF2, PRDM9, PBX3, MAFB, CDK8, MED1, TERF1, MYB, SMAD1, EVI1, BCL11A, SP1, NIPBL, REST, ZNF479, ATF7, TCF3, BCOR, MBD2, SMC3, MLLT1, STAG1, NFATC3, MEF2B, ZNF207, FOXA2, EBF1, MEIS1, TBL1X, E2F8, GTF2B, WT1, CDK9, KDM1A, YY1, RELA, TARDBP, SP140, ZFP36, SKIL, HIF1A, GATA3, BATF, MAF1, TAL1, MAX, SPIB, ZNF143, BCL11B, NCOA3, NR2F1, TP53, PKNOX1, ZNF687, MED, ZNF334, NFKB1, MYOD1, TBX21, BHLHE40, ZNF445, TAF1, RNF2, IKZF2, BRD4, NOTCH3, CUX1, RUNX1-3
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 22
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156299,
- Related loop:
chr21:31075000-31100000~~chr21:31325000-31350000,
chr21:31175000-31200000~~chr21:31325000-31350000,
chr21:31200000-31225000~~chr21:31300000-31325000,
chr21:31200000-31225000~~chr21:31325000-31350000,
chr21:31225000-31250000~~chr21:31325000-31350000,
chr21:31300000-31325000~~chr21:31575000-31600000,
chr21:31325000-31350000~~chr21:31425000-31450000,
chr21:31325000-31350000~~chr21:31500000-31525000,
chr21:31325000-31350000~~chr21:31550000-31575000,
chr21:31325000-31350000~~chr21:31575000-31600000,
chr21:31325000-31350000~~chr21:31600000-31625000,