- Basic information
- CohesinDB ID: CDBP00416544
- Locus: chr21-31334391-31335137
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Data sourse: GSE67783, GSE86191, GSE25021, GSE206145, GSE83726, GSE131606
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Cell type: MCF-7, RPE, RH4, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 42%,
"5_TxWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, XBP1, FOXA1, SUZ12, ZFP64, IKZF3, ZNF467, ZNF121, ETV1, ESR1, ZNF561, CTCF, BAF155, KLF1, ZBTB20, MNT, E2F1, ZNF528, PDX1, TFAP2C, GLIS1, BRD1, MYCN, ZBTB17, ZBTB48, ZSCAN5A, ERG2, ERG, ZNF341, MYC, SMARCA4, RAD21, FOXP2, GABPA, XRCC5, NKX3-1, ARNTL, NR3C1, CEBPB, EZH2, FEZF1, GRHL2, KLF17, GATA2, ZNF182, NKX2-2, ZFX, ZNF770, PRDM10, CREBBP, RUNX2, NRF1, ARNT, ZEB2, MAFB, FOS, MED1, ZXDB, MAFK, REST, ASH2L, FOXP1, SMC3, ELL2, STAG1, FOXA2, RBBP5, ZNF600, ZNF692, WT1, YY1, RELA, ZIC2, HIF1A, GATA3, MAX, ZNF449, ZNF143, NRIP1, NCOA3, NR2F1, MYOD1, BRD2, AR, RXR, EGLN2, BRD4, MAZ
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156299,
- Related loop:
chr21:31075000-31100000~~chr21:31325000-31350000,
chr21:31175000-31200000~~chr21:31325000-31350000,
chr21:31200000-31225000~~chr21:31325000-31350000,
chr21:31225000-31250000~~chr21:31325000-31350000,
chr21:31325000-31350000~~chr21:31425000-31450000,
chr21:31325000-31350000~~chr21:31500000-31525000,
chr21:31325000-31350000~~chr21:31550000-31575000,
chr21:31325000-31350000~~chr21:31575000-31600000,
chr21:31325000-31350000~~chr21:31600000-31625000,