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Basic information

CohesinDB ID: CDBP00416551

Locus: chr21-31351023-31353142

Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE104888, GSE72082, GSE86191, ENCSR000BSB, GSE110061, GSE129526, GSE111913, ENCSR000BLY, GSE25021, GSE206145, GSE85526, GSE206145-NatGen2015, GSE121355, GSE68388, GSE130135, ENCSR703TNG, GSE131606, GSE115602

Cell type: MCF-7, RPE, Fibroblast, HCT-116, HEKn, HEK293T, SK-N-SH, RT-112, HuCC-T1, DKO

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 11% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.878

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 59% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 46%, "7_Enh": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, PGR, ZNF660, ZSCAN5C, MEIS2, PATZ1, FOXA1, PBX2, INSM2, NFIC, ATF3, ZNF362, ZBTB44, CHD7, IKZF3, ZNF189, SMARCE1, ZNF467, ZNF629, ZNF506, ELF1, TRIM28, TEAD1, KLF6, ETV1, SNAI2, ZNF217, ESR1, HNF1B, ZNF561, JUN, TCF12, TAF3, EP300, KLF1, BAF155, MNT, ZBTB20, GATA6, LMO1, DPF2, TEAD4, ZNF92, TFAP2C, GLIS1, CHD8, ZNF263, POU5F1, MYCN, CTBP1, ZSCAN21, ZBTB48, ERG, ZBTB21, HOXC5, ZBTB8A, MYC, SMARCA4, FOXP2, RAD21, GRHL3, RXRA, NKX2-1, BATF3, APC, STAT3, RCOR1, ZNF639, VDR, ARNTL, ZNF750, ESRRA, CEBPB, FEZF1, GRHL2, TRPS1, EHF, IRF1, KLF17, HDAC2, GATA2, ZNF146, FLI1, SMARCA5, MRTFB, NCOA2, ZNF554, RUNX1, SMC1A, CBX1, ZMYM2, SIN3A, ZNF534, AFF4, SMAD3, ZNF770, SMARCC1, PRDM10, CREBBP, ZNF35, ZXDC, RUNX2, GATA4, OSR2, ZNF184, PBX4, NFIB, DAXX, ZBTB10, NRF1, ZEB2, FOXM1, SMARCB1, CDK8, FOS, MED1, ZEB1, ZNF558, ZXDB, MYB, ZMYM3, NIPBL, SP1, GSPT2, TFAP2A, REST, RBM25, CTBP2, PHIP, GLIS2, MBD2, FOXP1, BCOR, FOXA2, PAF1, ZNF600, ZNF692, WT1, CDK9, HOXB13, KDM1A, YY1, RELA, JUNB, ZIC2, HIF1A, GATA3, TAL1, MAX, NRIP1, HAND2, ZFP69B, KLF4, SP7, CEBPG, NR2F2, NR2F1, TCF7L2, KDM5B, TP53, PKNOX1, ZNF547, ELF3, BRD2, TBX21, BHLHE40, AR, YAP1, ZNF324, ZBTB42, NCOR1, BRD4, JUND, MAZ, ADNP, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): TIAM1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 12

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000156299,

eachgene

Deatailed information for cohesin site CDBP00416551