- Basic information
- CohesinDB ID: CDBP00416553
- Locus: chr21-31358007-31358278
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Data sourse: ENCSR000BLD, GSE86191, GSE55407
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Cell type: H1-hESC, HCT-116, THP-1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 79%,
"14_ReprPCWk": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, ZNF426, ZNF697, ZSCAN5C, SOX2, MEIS2, XBP1, HNF1A, PATZ1, FOXA1, MLL4, ZFHX2, TFAP4, ATF3, NFIC, INSM2, ZC3H8, ZNF362, ZBTB5, RUNX3, ZFP64, CHD7, ZNF189, PAX5, TP63, CDX2, MAF, ZNF629, KLF5, ELF1, TEAD1, TRIM28, KLF6, SNAI2, NFE2L2, ETV1, ESR1, HNF1B, TP73, OCA2, JUN, CTCF, TCF12, EP300, KLF1, MNT, LMO1, GATA6, DPF2, SOX4, IRF4, RAD51, E2F1, ZNF528, SMC1, TEAD4, PDX1, TFAP2C, EED, RBPJ, GLIS1, POU2F2, CHD8, TOP2A, CTBP1, MTA2, ZSCAN21, ZBTB48, ZNF317, STAT1, SRF, NBN, ERG2, HOXC5, ERG, ZBTB21, ZNF341, ETS1, MYC, NFKB2, SMARCA4, TSHZ1, RAD21, FOXP2, LHX2, GRHL3, RXRA, NKX2-1, PROX1, BATF3, GABPA, STAT3, APC, ZNF398, IKZF1, RCOR1, ZNF639, ARNTL, VDR, NR3C1, CEBPB, ESRRA, STAT5B, KMT2A, CREB1, EZH2, KLF8, GRHL2, FEZF1, SPI1, EHF, IRF1, KLF17, HDAC2, GATA2, FLI1, ZNF490, RELB, ZC3H11A, ZNF554, RUNX1, SMC1A, BCL6, NKX2-2, EZH2phosphoT487, AFF4, SIN3A, ZFX, POU4F2, SMAD3, ERG3, TRIM22, SMARCC1, PRDM10, ZNF18, CREBBP, ZNF35, NOTCH1, ZNF384, RUNX2, GATA4, OSR2, ZNF184, PBX4, DAXX, ARNT, NRF1, ATF2, ZEB2, ZNF518A, PBX3, CBFA2T3, ZNF10, FOS, CDK8, SMARCB1, FOXM1, MED1, ICE2, ZEB1, SPDEF, ZNF558, MYB, SCRT2, PIAS1, NR1H2, KLF9, STAT5A, USF1, NIPBL, SP1, BCL11A, HNF4A, ARID2, REST, POU2F3, ATF7, PHIP, SMC3, ELL2, ZNF34, STAG1, MLLT1, ZNF394, NFATC3, MEF2B, CBX3, FOXA2, EBF1, TBL1X, PAF1, SS18, ZNF600, ZNF692, ZSCAN16, ZNF30, MEF2C, CDK9, YY1, RELA, TARDBP, JUNB, TCF4, HIF1A, SKIL, OTX2, GATA3, BATF, MAX, ZNF143, KLF4, BCL11B, SP7, TCF7L2, NR2F1, KDM5B, TP53, PKNOX1, NFKB1, MYOD1, ZSCAN22, EGR2, ELF3, BRD2, TBX21, BHLHE40, AR, ZNF579, ZNF324, EGLN2, ZNF366, EGR1, HSF1, MYNN, IKZF2, BRD4, JUND, MAZ, ZNF440, ZSCAN23, BRCA1, FOSL2
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 0
- Related genes and loops