- Basic information
- CohesinDB ID: CDBP00416554
- Locus: chr21-31363680-31364050
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Data sourse: GSE206145, GSE73207
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Cell type: RPE, TF-1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 62%,
"7_Enh": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, ZNF660, SOX2, PATZ1, FOXA1, MLL4, ZFHX2, INSM2, ATF3, NFIC, ZFP64, ZNF362, CHD7, PRDM1, ZNF189, TP63, CDX2, MAF, ZNF506, ZNF629, TEAD1, TRIM28, ETV1, SNAI2, KLF6, KLF10, LMO2, ESR1, HNF1B, CTCF, TCF12, JUN, EP300, ARID5B, BAF155, LMO1, ZBTB20, SOX4, IRF4, FOSL2, E2F1, TEAD4, ZNF92, ZNF175, TFAP2C, NANOG, CHD8, POU5F1, CDK7, ZNF317, ZBTB17, ZBTB48, ZSCAN21, STAT1, DUX4, SRF, ERG2, ERG, PAX6, HOXC5, PBX1, ASCL1, ZNF341, NFKB2, MYC, ONECUT1, SMARCA4, RFX1, RAD21, LHX2, GRHL3, RXRA, NKX2-1, GABPA, STAT3, APC, NKX3-1, RCOR1, ZNF639, ARNTL, VDR, NR3C1, ESRRA, CEBPB, STAT5B, KMT2A, EZH2, KLF8, SPI1, EHF, IRF1, KLF17, GATA2, SSRP1, SIX2, FLI1, MRTFB, ZIM3, ZNF554, RUNX1, SMC1A, CEBPA, CRY1, AFF4, ZFX, SMAD3, ERG3, TWIST1, PRDM10, SMARCC1, CREBBP, ZNF35, NOTCH1, ZNF384, RUNX2, GATA4, OSR2, ZNF184, PBX4, DAXX, ARNT, NRF1, ZEB2, PBX3, SUPT5H, CDK8, FOS, MED1, ZEB1, MYB, PIAS1, KLF9, ZNF22, BCL11A, NIPBL, SP1, REST, RBM25, PHIP, TCF3, SMC3, ZNF394, MEF2B, CBX3, SS18, PAF1, ZNF600, ZNF692, ZBTB33, CDK9, KDM1A, YY1, RELA, JUNB, HIF1A, OTX2, GATA3, TAL1, MAX, SPIB, GATA1, CBX2, KLF4, SP7, GFI1B, NR2F2, TCF7L2, KDM5B, TP53, PKNOX1, NFKB1, EGR2, ELF3, BRD2, TBX21, BHLHE40, AR, ZBTB16, ZBTB40, ZNF366, HSF1, NCOR1, BRD4, JUND, MAZ, ZSCAN23, ZNF24, RUNX1-3
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 0
- Related genes and loops