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Basic information

CohesinDB ID: CDBP00416558

Locus: chr21-31372187-31373155

Data sourse: GSE104888, GSE67783, GSE86191, ENCSR000BSB, GSE129526, GSE111913, GSE206145

Cell type: RPE, RT-112, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: NIPBL,SA1,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 59% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 66%, "14_ReprPCWk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, GLIS1, FOSL1, CHD8, ZSCAN5C, SS18, ZFX, ZNF600, NME2, WT1, MAFF, ZBTB48, FOXA1, SMAD3, ZSCAN5A, ERG3, ERG2, ZFHX2, PRDM10, HOXC5, YY1, RELA, ZNF384, JUNB, ATF3, ZC3H8, RUNX2, SMARCA4, OSR2, RAD21, GRHL3, IKZF3, ZIC2, DAXX, NKX2-1, ZNF189, APC, PAX5, FOXM1, STAT3, ZNF143, CDK8, FOS, NKX3-1, MED1, ICE2, VDR, ZNF750, TEAD1, NR2F2, TFAP2C, TCF7L2, EZH2, ESR1, ZBTB6, C11orf30, CTCF, BRD2, MAFK, NIPBL, JUN, SP1, IRF1, IRF4, BRD4, PHIP, JUND, MAZ, PRDM6, ZNF350, ZNF76, PDX1, ZNF316

Target gene symbol (double-evidenced CRMs): TIAM1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 18

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000156299,

eachgene

Deatailed information for cohesin site CDBP00416558