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Basic information

CohesinDB ID: CDBP00416559

Locus: chr21-31373970-31375053

Data sourse: GSE206145, GSE67783, ENCSR230ZWH, GSE86191

Cell type: Liver, HCT-116, HSPC, HEK293T

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: NIPBL,SA1,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 59% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 69%, "14_ReprPCWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: GLIS1, PGR, NANOG, ZNF554, POU5F1, ZNF263, ZFX, ZNF600, ZSCAN21, GTF2B, ZBTB17, ZSCAN5A, ZSCAN16, WT1, ZBTB48, PATZ1, ZNF574, ZNF692, ZNF30, FOXA1, TBP, PRDM10, ERG, YY1, ZNF18, ZNF35, ASCL1, ZNF341, MYC, EOMES, OSR2, ZNF184, ZNF610, RAD21, GRHL3, IKZF3, ZIC2, PRDM1, PRDM9, GABPA, ZNF189, MAX, PAX5, ZNF143, ZNF467, NR3C1, SP7, NCOA3, NR2F2, ZNF680, EZH2, GRHL2, ZNF334, MYOD1, ZNF561, BRD2, CTCF, KLF1, AR, KLF17, PAX8, ZNF324, IRF4, ZNF146, ZBTB42, SIX2, BRD4, PHIP, MAZ, ZNF528, ZSCAN23, ZIM3, PRDM6, STAG1

Target gene symbol (double-evidenced CRMs): TIAM1,SCAF4,HUNK

Function elements

Human SNPs: .

Number of somatic mutations (coding): 20

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000156299, ENSG00000156304, ENSG00000142149,

eachgene

Deatailed information for cohesin site CDBP00416559