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Basic information

CohesinDB ID: CDBP00416561

Locus: chr21-31381978-31382484

Data sourse: GSE73207

Cell type: TF-1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 59% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 76%, "14_ReprPCWk": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, NFATC3, CBFA2T2, HDAC1, LDB1, CREM, MEIS1, TOP2A, MEIS2, MTA2, DUX4, STAT1, NONO, PBX2, ERG, KDM1A, LYL1, NEUROD1, NFIC, SMARCA4, GATA4, ARID1B, GRHL3, GATA3, ZEB2, GABPA, TAL1, CBFA2T3, FOXM1, SMARCE1, GATA1, CDK8, NFE2, RCOR1, NR3C1, CEBPB, ESRRA, GFI1B, PML, TRIM28, MYB, NR2F2, CEBPD, SMAD1, EZH2, LMO2, TP53, TCF7L2, PKNOX1, NCOA1, ZNF879, STAT5A, KLF16, TCF12, BCL11A, SPI1, HES1, LMO1, EP300, GATA6, KLF1, DPF2, HDAC2, GATA2, ZBTB40, CCNT2, TRIM24, ZSCAN29, SOX6, SIX2, ATF7, NCOR1, RNF2, BRD4, BCOR, PRDM6, ZNF528, TEAD4, ZNF891

Target gene symbol (double-evidenced CRMs): TIAM1,SCAF4,HUNK

Function elements

Human SNPs: .

Number of somatic mutations (coding): 8

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000156299, ENSG00000156304, ENSG00000142149,

eachgene

Deatailed information for cohesin site CDBP00416561