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Basic information

CohesinDB ID: CDBP00416566

Locus: chr21-31394630-31394826

Data sourse: GSE120943, GSE98367

Cell type: Monocytes, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 59% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 65%, "7_Enh": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, ZNF468, CTNNB1, CHD8, SMC1A, FOXA2, POU5F1, EBF1, MYCN, SOX2, ZFX, NME2, XBP1, TOP2A, WT1, TEAD4, ZNF134, CDK9, ZNF596, TBP, YY1, RELA, NOTCH1, MYC, SMARCA4, OSR2, GRHL3, GABPA, TAL1, MAX, ZSCAN4, ZNF10, ZNF143, IKZF1, MITF, BCL11B, TEAD1, TRIM28, MYB, CREB1, KMT2A, TFAP2C, EZH2, LMO2, PKNOX1, OCA2, SETDB1, CTCF, SPI1, GSPT2, AR, SIX2, HSF1, NOTCH3, BRD4, PHIP, TCF3, ZIM3, PDX1, AHR, EED

Target gene symbol (double-evidenced CRMs): SCAF4,TIAM1,HUNK

Function elements

Human SNPs: .

Number of somatic mutations (coding): 10

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000156299, ENSG00000156304, ENSG00000142149,

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Deatailed information for cohesin site CDBP00416566