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Basic information

CohesinDB ID: CDBP00416569

Locus: chr21-31397471-31398996

Data sourse: GSE206145, GSE62063, ENCSR000EHX, ENCSR000BLY

Cell type: SK-N-SH, HEK293T, Ramos

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: NIPBL,SA1,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 59% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 43%, "7_Enh": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, ZNF660, SOX2, MEIS2, PATZ1, FOXA1, ZNF221, PBX2, MLL4, ZNF529, INSM2, NFIC, ZFP64, ZNF362, ZBTB44, PRDM1, IKZF3, CHD7, ZNF189, MZF1, TP63, ZNF320, ZNF467, ZNF629, KLF5, TEAD1, TRIM28, KLF10, LMO2, OCA2, PITX3, ZNF561, ZNF577, CTCF, TCF12, EP300, ARID5B, LMO1, GATA6, IRF4, ZNF528, ZNF350, ZNF280A, PDX1, RBPJ, TFAP2C, GLIS1, POU2F2, CHD8, ZNF263, BRD3, CDK7, MYCN, ZSCAN21, ZBTB17, ZBTB48, ERG2, SP4, ERG, PBX1, ZNF341, MYC, ONECUT1, SMARCA4, ZNF2, RAD21, GRHL3, GABPA, RCOR1, NFE2, ZNF639, ARNTL, NR3C1, CEBPB, STAT5B, KMT2A, EZH2, KLF8, FEZF1, EBF3, SPI1, ZNF664, GATA2, ZNF766, RUNX1, ZNF534, ZNF214, ZNF770, CBX8, ERG3, ZNF18, PRDM10, SMARCC1, RARA, ZNF35, NOTCH1, ZNF384, GATA4, OSR2, ZNF184, NFIB, ATF2, ZEB2, ZNF518A, PBX3, FOXM1, SP2, SUPT5H, CDK8, MAFB, MED1, ZNF558, ZXDB, MYB, SCRT2, PIAS1, ZNF680, ZNF37A, ZNF22, MAFK, BCL11A, SP1, POU2F3, ATF7, PHIP, TCF3, PRDM6, ZNF337, ZNF34, ZNF394, FOXA2, EBF1, ZNF600, ZNF692, GTF2B, WT1, ZNF30, ZSCAN16, MAFF, ZNF662, ZNF574, CDK9, HOXB13, KDM1A, YY1, ZNF610, ISL1, OTX2, GATA3, ZNF519, TAL1, GATA1, HAND2, CEBPG, ZFP69B, SP7, BCL11B, ZNF544, TCF7L2, TP53, PKNOX1, PHOX2B, BRD2, TBX21, AR, ZNF324, ZNF366, ZBTB42, MAML3, ZBTB26, RNF2, BRD4, SCRT1, MAZ, ZNF440, ZSCAN23, ZNF24, ZNF316

Target gene symbol (double-evidenced CRMs): TIAM1,HUNK,SCAF4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 20

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000156299, ENSG00000156304, ENSG00000142149,

eachgene

Deatailed information for cohesin site CDBP00416569