- Basic information
- CohesinDB ID: CDBP00416573
- Locus: chr21-31410653-31411166
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Data sourse: ENCSR000EAC, ENCSR000DZP, GSE50893
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Cell type: GM12878, SNYDER
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC3,Rad21,SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 50%,
"7_Enh": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZSCAN5C, NME2, MEIS2, XBP1, PATZ1, FOXA1, SUZ12, PBX2, ZFHX2, HDGF, ATF3, NFIC, THAP1, PRDM1, PAX5, ZSCAN4, ZNF736, ZNF467, TRIM28, BCLAF1, ETV1, RBM39, ESR1, JUN, CTCF, TCF12, EP300, MNT, LMO1, DPF2, IRF4, GLI4, SOX6, ZNF528, YBX1, POU2F2, CHD8, NANOG, POU5F1, MYCN, ZNF239, ZNF263, ZNF778, CTBP1, ZSCAN21, ZBTB1, ZBTB48, ZSCAN5A, MTA2, NONO, DDX5, NBN, ERG2, PHB2, SP4, ERG, EZH1, MCM5, MYC, GABPA, IKZF1, VDR, KMT2A, CREB1, EZH2, SPI1, HES1, IRF1, HDAC2, SSRP1, GATAD2B, SIX2, FLI1, ATM, SMARCA5, RELB, RUNX1, SMC1A, HDAC1, ZNF707, CRY1, ZFX, ZNF534, TBX3, ERG3, TRIM22, ZNF18, NOTCH1, OSR2, ARNT, ZNF48, PBX3, CDK8, MED1, TERF1, MYB, STAT5A, NIPBL, BCL11A, GSPT2, ATF7, TCF3, FOXP1, SALL1, SMC3, MLLT1, NFATC3, MEF2B, MEIS1, NFATC1, WT1, ZBTB33, CDK9, BCL3, ZKSCAN1, YY1, RELA, TARDBP, ZNF282, MCM3, SP140, HIF1A, SKIL, GATA3, ZNF143, BCL11B, NR2F1, TP53, PKNOX1, ZSCAN22, EGR2, TBX21, BHLHE40, AR, HSF1, IKZF2, BRD4, CLOCK, MAZ
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops